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2 edition of Molecular evolution of pituitary growth hormone found in the catalog.

Molecular evolution of pituitary growth hormone

Zoitsa Maniou

Molecular evolution of pituitary growth hormone

by Zoitsa Maniou

  • 48 Want to read
  • 37 Currently reading

Published .
Written in English


Edition Notes

D.Phil. 2003 BLDSC DXN.

Statementby Zoitsa Maniou.
SeriesSussex theses ; S 5459
The Physical Object
Pagination190p. :
Number of Pages190
ID Numbers
Open LibraryOL18963754M

  The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in , there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the ?id=OFFW68kMpFIC.

Analysis of the carcases of rats shows that the composition of the gain of animals treated with anterior pituitary growth hormone is closely similar to their initial composition, while the composition of the control animals shows changes that are to be expected with age.-W. ://   Title: Molecular Cloning of Grass Carp Growth Hormone Receptor and Its Functional Interaction with Silver Carp Growth Hormone VOLUME: 16 ISSUE: 3 Author(s):Wei Hu, Xia Chen, Gusong Yu, Yan Chen, Yan Shen, Ying Zhang and Yi Gong Affiliation:Shanghai Institutes for Biological Sciences, Graduate University of the Chinese Academy of Sciences, Shanghai , P.R. ?genre.

Two molecular forms of growth hormone, GHs I were isolated from a culture medium of the eel pituitary (Anguilla japonica). The complete amino acid sequence of GH I was determined in the From the results mentioned above, 14 of the 41 patients with MPHD had pan-pituitary hormones (LH, FSH, TSH, ACTH) deficiency, only one had isolated growth hormone ://


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Molecular evolution of pituitary growth hormone by Zoitsa Maniou Download PDF EPUB FB2

The sequence of growth hormone (GH) is generally strongly conserved in mammals, but episodes of rapid change occurred during the evolution of primates and artiodactyls, when the rate of GH evolution apparently increased substantially.

As a result the sequences of higher primate and ruminant GHs differ markedly from sequences of other mammalian :// Request PDF | Episodic Molecular Evolution of Pituitary Growth Hormone in Cetartiodactyla | The sequence of growth hormone (GH) is generally strongly conserved in mammals, but episodes of rapid Abstract.

Growth hormone (GH), secreted by anterior pituitary somatotroph cells, binds to hepatic GH receptors, initiating several intracellular signaling pathways resulting in the generation of insulin-like growth factor (IGF)-1, cytoskeletal changes, alterations in glucose metabolism, and modulation of cell proliferation :// Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family.

Functional implication in the regulation of growth hormone secretion Summary 1. The pituitary hormones can be divided into 4 families; within each the members are structurally related and have probably evolved from a common ancestor by a process of gene duplication and divergence.

Recent structural studies have revealed much about the evolution of proteins. The roles of point mutation, gene duplication and partial gene duplication in molecular evolution have Abstract.

The incidence of defects in growth hormone (GH) synthesis resulting in short stature is betweenandlive births (1,2).Most of these cases are sporadic, without a known or proposed molecular Since the publication of the second edition of The Pituitary, inthere have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary :// Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family.

Functional implication in the regulation of growth hormone secretion in Journal of Molecular Endocrinology Pituitary growth hormone and prolactin, together with the homologous placental hormones, comprise a family of related protein hormones.

Complete or partial amino acid sequences of seven mammalian growth hormones, six mammalian prolactins and one placental lactogen are available, and have been compared.

A phylogenetic tree has been constructed which describes the relationships within the :// The goal of the project is to construct a molecular phylogenetic tree of the growth hormone and prolactin family on the basis of sequence comparisons and to semi-quantify the phylogenetic distance of animals using ratios of amino acid changes.

Although a substantial amount of structural information is now available on growth hormones and prolactins, it is still limited to mammalian and The molecular evolution of pituitary growth hormone prolactin and placental lactogen: A protein family showing variable rates of evolution 10W/abstract.

The placental growth-hormone-like proteins of primates show a similar pattern. It is argued that the bursts of evolution seen for growth hormone are a consequence of selection and that this may reflect changes in the functions of the hormone additional to its basic growth-promoting actions.

PMID: [Indexed for MEDLINE] MeSH terms. Animals Montero M, Yon L, Kikuyama S, Dufour S, Vaudry H. Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family.

Functional implication in the regulation of growth hormone secretion. J Mol Endocrinol. ;– JME [pii]. CrossRef PubMed Google Scholar Montero M, Yon L, Kikuyama S, Dufour S, Vaudry H. Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family.

Functional implication in the regulation of growth hormone secretion. J Mol Sequences of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication.

Proc Natl Acad Sci U S A. Apr; 68 (4)– [PMC free article] Fiddes JC, Seeburg PH, DeNoto FM, Hallewell RA, Baxter JD, Goodman HM. Structure of genes for human growth hormone and chorionic :// Read the latest chapters of Fish Physiology atElsevier’s leading platform of peer-reviewed scholarly literature   History.

Growth hormone (GH) was first isolated inand the primary structures of bovine and ovine GHs were determined in early tin (PRL) was discovered in rabbits and pigeons as the milk-secreting factor aroundand later confirmed in humans in Somatolactin (SL) was first isolated and characterized in the early far, SL has been found only in ://   SECTION I: Brain Hormones.

N.M. Sherwood, et al., Molecular Evolution of Growth Hormone-Releasing Hormone and Gonadotropin-Releasing Hormone. Lederis, et al., Corticotropin-Releasing Factors Acting on the Fish Pituitary: Experimental and Molecular Analysis.

Urano, et al., Expression of the Vasotocin/Isotocin Gene Family in Fish. SECTION II: Pituitary Hormone Molecular Endocrinology examines basic principles in molecular endocrinology using selected examples.

It looks at the molecular aspects of hormone action, from hormone-receptor interactions to second messenger generation, gene induction, and post-transcriptional :// Pituitary growth hormone (GH), like several other protein hormones, shows an unusual episodic pattern of molecular evolution in which sustained bursts of rapid change are imposed on long periods.

Molecular Evolution of Growth Hormone (GH) in Cetartiodactyla: Cloning and Characterization of the Gene Encoding GH from a Primitive Ruminant, the Chevrotain (Tragulus javanicus) General and Comparative Endocrinology, Vol.No. 1  Sequences of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication.

Proc Natl Acad Sci U S A. Apr; 68 (4)– [PMC free article] Bewley TA, Dixon JS, Li CH. Sequence comparison of human pituitary growth hormone, human chorionic somatomammotropin, and ovine pituitary growth Author: Maniou Z. Search worldwide, life-sciences literature Search.

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